褪黑素melatoninMSDS

SAFETY DATA SHEET Section 1 - Chemical Product and Company Identification Name:Melatonin Producer: Luotian Hengxingyuan Chemecial Co.,ltd Composition Batch No.: HXY100510 Manufacture Date:2010.05.10  Expiry Date:2012.05.09 Section 2 - Hazards Identification Hazard and Hurt to Health:May cause eye and skin irritation. May cause respiratory and digestive tract irritation. May cause adverse reproductive effects based upon animal studies. The toxicological properties of this material have not been fully investigated. Section 3 - First Aid Measures Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid if irritation develops or persists. Flush skin with plenty of soap and water. Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid. Inhalation: Remove from exposure and move to fresh air immediately. Get medical aid if cough or other symptoms appear. Notes to Physician: Treat symptomatically and supportively. Section 4- Fire Fighting Measures General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Flash Point: Not available. Autoignition Temperature: Not available. Explosion Limits, Lower:Not available. Upper: Not available. NFPA Rating: Not published. Section 5- Accidental Release Measures General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Section 6 - Handling and Storage Handling: Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Storage: Store in a cool, dry place. Store in a cool, dry, well-ventilated area away from incompatible substances. Section 7 - Exposure Controls, Personal Protection Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits Chemical Name ACGIH NIOSH OSHA - Final PELs Melatonin none listed none listed none listed OSHA Vacated PELs: Melatonin: No OSHA Vacated PELs are listed for this chemical. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 8 - Physical and Chemical Properties Physical State: Leaflets Appearance: white to yellow Odor: None reported. pH: Not available. Vapor Pressure: Not available. Vapor Density: Not available. Evaporation Rate:Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point:117.00 - 120.00 deg C Decomposition Temperature:Not available. Solubility: Not available. Specific Gravity/Density:Not available. Molecular Formula:C13H16N2O2 Molecular Weight:232.28 Section 9 - Stability and Reactivity Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials, strong oxidants. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported. Section 10 - Disposal Considerations Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. RCRA P-Series: None listed. RCRA U-Series: None listed. Section 11 - Toxicological Information RTECS#: CAS# 73-31-4: AC5955000 LD50/LC50: CAS# 73-31-4: Oral, mouse: LD50 = 1250 mg/kg; Oral, rat: LD50 = >3200 mg/kg; Carcinogenicity: CAS# 73-31-4: Not listed by ACGIH, IARC, NTP, or CA Prop 65. Epidemiology: Reproductive effects have been observed. Teratogenicity: No data available. Reproductive Effects: No data available. Mutagenicity: No data available. Neurotoxicity: No data available. Other Studies: Section 12 - Ecological Information No information available. Section 13 - Transport Information Not regulated as a hazardous material Section 14 - Normal Information Atmosphere pollution limit : No ref Mark of Irritation agent: No