NetworkpharmacologyforFangJiomicsapproachNetworkpharmacologyAnewperspectivetounderstandprincipleofdrugcombinationinTraditionalChineseMedicine?君-King臣-Minister佐-Assistant使-AmbassadorTheInter-ModuleNetworkDifferentRolesoftheGeneModules&theircooperationeffectsTheinformationtodeliverNetworkcouldbedrugtargetNetworkpharmacologybelongstoadivisionofsystemsbiologyandprovidesasynergisticstrategiesandcomprehensiveapproachestorevealtheinnernetworkrelationshipsbetweenmoderndrugsandhumanbodyfunction.Notably,itisveryhelpfulforscreeningactivecomponents,exploringpotentialtargetsandclarifyingcomplexmechanismsinTCMviahighthroughputtechnologiesofnetworkpharmacologyGeneModuleDatabaseProteinNetworkPathwayGeneOntologymiRNATargetGeneGeneModuleDatabaseFigure1.TheframeworkoftheFangjiomicsstudyofXKATable1.Thetop10compoundswiththemosttargetsFigure4A.Thetopcompound-target–pathwaynetworksofXKAinthetreatmentofT2D.(A).Thecompound-target–pathwaynetworkswithcompoundsidentifiedbyLC-MSanalysis(NCA)展望通过生物学网络中节点的连接和关系来
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网络特性，进一步阐明药物作用机制通过网络药理学的研究来寻找、优化和确认靶点，对新药的发现具有重要的指导意义通过网络药理学分析，可以预测和分析药物副作用产生的可能性和药物作用的新靶点
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