倍他米松_百度百科（Betamethasone _ Baidu Encyclopedia）

倍他米松_百度百科（Betamethasone _ Baidu Encyclopedia） 倍他米松_百度百科(Betamethasone _ Baidu Encyclopedia) Betamethasone _ Baidu Encyclopedia Baidu home page | login news page Post Bar MP3 photo video library. Help set up home page, natural culture, geography, history, life, society, art, character, economy, science, sports, dream of Red Mansions, Expo Betamethasone name card. Betamethasone is glucose metabolism and anti-inflammatory effects of hydrocortisone is strong, 15 times of hydrocortisone sodium retention, but for more than one hundred times of hydrocortisone in primary adrenal cortical hypofunction, together with glucocorticosteroids for replacement therapy. It is also applicable to low renin, low aldosterone syndrome and orthostatic hypotension due to autonomic neuropathy. Catalog brief introduction Drug name Ingredients Character Indication preparation Specifications usage and dosage Adverse reaction taboo Matters needing attention Medication for pregnant women and lactating women Medication for children Senile medication Drug interaction Treatment of leukemia Treatment of rheumatism Overdose pharmacology and toxicology Pharmacokinetics Storage Packing Term of validity Implementation standards Approval number Brief introduction of production enterprises Drug name Ingredients Character Indication preparation Specifications usage and dosage Pay attention to adverse reactions of taboo leukemia matters for pregnant and lactating women medication medication for children aged drug drug interactions in the treatment of rheumatism treatment drug overdose of pharmacology and toxicology pharmacokinetics storage packaging effective period standard approval number production enterprise Edit this paragraph introduction Betamethasone, its structure: An efficient halogen containing corticosteroid drugs on glucose metabolism, can reduce the pathological changes of organism caused by damage of stimulation, and high curative effect and the anti-inflammatory effect of dexamethasone is strong, the side effect is small, but the treatment of systemic lupus erythematosus, rheumatoid arthritis, asthma and other serious illness in the international clinical widely used. Edit the drug name in this paragraph Generic name: name of commodity: injection of betamethasone with English Name: Betamethasone Sodium Phosphate for Injection Pinyin: Zhusheyong Beitamisong Linsuanna betamethasone Alias: beta - class pine, Betameth, Betasolon, Celestan, Celestone, Rinderon. Molecular formula: C22H29O5F Molecular weight: 392.47 character: tablet, injection. Edit this paragraph Main ingredients: betamethasone sodium phosphate chemical name: 16 beta beta alpha methyl -11, 17 21-, three -9 alpha - hydroxy fluoride pregnane -1, 4- -3,20- two -21- diene ketone Molecular formula: C22H28FNa2O8P molecular weight: 516.41, the auxiliary material for mannitol, injection water. Edit paragraph character This product is white or white loose loose lump or powder. Edit this paragraph of indications Betamethasone isomers for dexamethasone, action and use with dexamethasone acetate, sodium and water retention effect and dose than the latter is small. Sugar metabolism and anti-inflammatory effects of hydrocortisone is strong, 15 times of hydrocortisone sodium retention, but for more than one hundred times of hydrocortisone in primary adrenal cortical hypofunction, together with glucocorticosteroids for replacement therapy. It is also applicable to low renin, low aldosterone syndrome and orthostatic hypotension due to autonomic neuropathy. Because this product may cause edema for oral, topical local coating treatment of seborrheic eczema, contact dermatitis, genital itching, anus. The thyroid gland is mainly used for allergic and autoimmune inflammatory diseases. It is now used in active rheumatism, rheumatoid arthritis, lupus erythematosus, severe bronchial asthma, severe dermatitis, acute leukemia, and so on. It is also used in the combined treatment of certain infections. Edit this paragraph preparation Betamethasone Sodium Phosphate Injection Injectiobe - tamethasoniPhospgatisNatrici: colorless transparent sterile aqueous solution, pH8 - 9, suitable for emergency. Of acute adrenal insufficiency, intramuscular or intravenous injection, 1, 10 - 80mg (according to the calculation of 1.3mg of this product is betamethasone, betamethasone LMG), at the beginning of 4 general 12mg, intraarticular injection, 1 - 0.2 1ml. Each 1ml containing betamethasone 4mg. Silica gel cement betamethasone suspension injection InjectioBe. TamethasoniAquosuspensa: for the sterile suspension, pH6.8 - 7.2. Each 5ml containing betamethasone sodium phosphate 15mg and betamethasone acetate 15mg. Intramuscular injection: 1ml per time, 1 times every 3 to 7 days. Joint cavity injection: 0.25-2ml at each time. Betamethasone sodium phosphate drops GuttaeBetahletha - soniPhosphatisNatrici:0.1% solution for treating allergic type of eye ear nose skin. Edit this paragraph specification 5.26mg (with betamethasone sodium phosphate, the equivalent of betamethasone 4mg.) Edit the usage of this paragraph Intramuscular injection or intravenous injection: 2-20mg per day, divided into medication. Before use, use proper amount of sterile injection and dissolve it with solvent. Edit this episode of adverse reactions Glucocorticoid replacement therapy in the application of physiological doses without obvious adverse reactions, adverse reactions occurred in the application of pharmacological doses, and dose and duration of treatment, and drug types, usage and administration route are closely related. The common adverse reactions are as follows: (1) long term use can cause side effects: iatrogenic Cushing syndrome face and body, weight gain, edema of lower limbs, purple lines, easy bleeding, wound healing, acne, menstrual disorders, brachial or femoral head ischemic necrosis, osteoporosis and fractures (including vertebral compression fractures, bone pathology fracture), muscle weakness, muscle atrophy, hypokalemia syndrome, gastrointestinal irritation (nausea, vomiting), pancreatitis, peptic ulceration or perforation, children's growth is inhibited, glaucoma, cataract, benign intracranial hypertension syndrome, IGT and diabetes increase. (2) the patient may have mental symptoms: euphoria, agitation, delirium, restlessness, disorientation, or inhibition. Mental symptoms include those who are prone to chronic wasting diseases and those who have previously had mental disorders. (3) concurrent infection is the main adverse reaction of adrenal cortex hormone. They are mainly fungi, tubercle bacillus, Staphylococcus, proteus, Pseudomonas aeruginosa and various herpes viruses. (4) glucocorticoid withdrawal syndrome. Sometimes in patients after discontinuation of dizziness, fainting tendency, abdominal or back pain, fever, anorexia, nausea, vomiting, muscle or joint aches, headaches, fatigue, weakness, after careful examination can exclude adrenal insufficiency and the resurgence of the disease, can be considered as dependent on glucocorticoid synthesis sign. Edit this paragraph taboo This product and other steroid hormones are forbidden. The following diseases were generally not used, special circumstances should be weighed, but should pay attention to disease progression may: serious mental illness (past or present) and epilepsy, active peptic ulcer disease, recent gastrointestinal anastomosis, fracture, wound healing, corneal ulcer, hyperadrenocorticism, hypertension, diabetes, pregnant women, antibacterial drugs can not control the infection such as chickenpox, measles, fungal infection, severe osteoporosis. Edit the notes in this paragraph (1) induced infection: under the action of hormone, the infection that has been controlled can be activated, and the most common is the recurrence of tuberculosis infection. Application of hormone can reduce tissue damage, reduce leakage, reduce the symptoms of infection in some infections, but also must be treated with antibiotics, effective close observation of changes in the short term after treatment, which should be rapid reduction and withdrawal. (2) the interference of diagnosis: glucocorticoid can make blood sugar, blood cholesterol and blood fatty acid, blood sodium level rise, and make the blood calcium and blood potassium drop. The influence of peripheral blood on the number of lymphocytes, eukaryotic cells and eosinophils and basophils decreased, and the number of multinucleated leukocytes and platelets increased, and the latter decreased. Chronic high doses of corticosteroids can cause skin tests to be false negative, such as tuberculin tests, tissue cyclosporine tests, and allergy skin tests. It can also reduce the uptake of thyroid 131I and weaken the response of thyroid stimulating hormone (TSH) to the release of TSH (TRH), which makes TRH excited and the experimental result is false positive. Results of interference with luteinizing hormone releasing hormone (LHRH) stimulation test. Reduced or sparse isotope images of the brain and bone. (3) the following conditions should be used with caution: heart disease or acute heart failure, diabetes, diverticulitis, emotional instability and psychotic tendencies, systemic fungal infection, glaucoma, liver damage, ocular herpes simplex, hyperlipidemia, hypertension, hypothyroidism (enhanced the effect of glucocorticoid), myasthenia gravis, osteoporosis osteoporosis, gastric ulcer, gastritis and esophagitis, renal damage or stones, such as tuberculosis. (4) follow-up examination: long-term use of glucocorticoids, should regularly check the following items: the test of blood and urine glucose or glucose tolerance, especially diabetes or diabetes tendency. Children should be regularly tested for growth and development. Eye examination, attention to cataract, glaucoma or eye infections. Serum electrolytes and fecal occult blood. The examination of hypertension and osteoporosis, especially in the elderly. Edit this paragraph for pregnant women and lactating women (1) medication during pregnancy: glucocorticoids can pass through the placenta. Animal experiments have confirmed that prenatal administration can increase the incidence of cleft palate, placental dysfunction, spontaneous abortion and intrauterine growth retardation. Human doses of glucocorticoids may increase placental dysfunction, neonatal weight loss, or stillbirth. (2) lactation medication: because of the excretion of glucocorticoids in the milk, it can cause adverse effects on infants, such as growth inhibition and adrenal cortical suppression. Pregnant and lactating women in the balance situation, as far as possible to avoid the use of. Edit this paragraph for child medication Pediatric long-term use of adrenal hormones, must be very careful. Edit this section of geriatric medication Elderly patients with high blood pressure and diabetes are prone to glucocorticoid. In elderly patients, especially in postmenopausal women, glucocorticoids are more likely to aggravate osteoporosis. Edit this episode of drug interaction The non steroidal anti-inflammatory drugs can enhance the ulcerogenic effect. It can enhance the hepatotoxicity of acetaminophen. In combination with amphotericin B or carbonic anhydrase inhibitors, can aggravate hypokalemia, long-term and carbonic anhydrase inhibitors in combination, prone to hypocalcemia and osteoporosis. The combination with protein anabolic hormone, can increase the incidence of edema, aggravate acne. Along with anticholinergic drugs (such as atropine) combined with long-term, can cause increased intraocular pressure. Such mental symptoms of tricyclic antidepressants can be caused by the increase. 7 and hypoglycemic drugs such as insulin combination, because can make the blood glucose of diabetic patients increased, should adjust the dosage of antidiabetic drug. According to the thyroid hormone can make its metabolic clearance rate increased, the thyroid hormone or antithyroid drugs and their combination, the dosage should be adjusted. Only with the contraceptive or estrogen preparations, can enhance the therapeutic effects and adverse reactions. I have combined with the strong heart glucoside, can increase the occurrence of digitalis toxicity and arrhythmia. Being combined with the efflux of potassium diuretic drugs, can cause severe hypokalemia, diuretic effect and the retention of water and sodium decreased diuretic. The combination of ephedrine and can enhance the metabolic clearance. Three combined with immunosuppressive agents, can increase the risk of infection, and may induce lymphoma or other lymphoproliferative diseases. To increase the metabolism and excretion of isoniazid in the liver, reduce the serum concentration and clinical efficacy of isoniazid. And mexiletine can promote in vivo metabolism, reduce blood concentration. With the increase of salicylate combination, can reduce the plasma concentrations of salicylic acid salt. And in combination with growth hormone, can inhibit the growth promoting effect of the latter. Edit this episode of leukemia treatment Leukemia is a malignant disease of hematopoietic tissue, also known as "cancer of the blood". The characteristics of bone marrow and other hematopoietic tissue in a large number of leukemia cells unlimited proliferation, and enter the blood, making normal blood cells was obviously inhibited, the disease of malignant disease of young people in the first place, the etiology is still unclear, the virus may be the major pathogenic factor, but there are many factors such as radiation, toxic chemicals (such as benzene) or drugs, genetic quality may be pathogenic factor. According to the degree of immaturity of leukemia cells and the natural course of leukemia, it is divided into two major categories: acute and chronic. Leukemia characterized by leukemia cells in bone marrow and other hematopoietic tissues were malignant, unlimited proliferation, infiltration of body tissues and organs, produce different symptoms; peripheral blood blood cell changes in quantity and quality. Each day, the marrow produces billions of new blood cells, most of them red blood cells. The leukemia cells produce more white blood cells than they actually need, and most white cells are immature and immature, and their survival is longer than normal. Although the white blood cells are large, they do not fight infections like normal white blood cells. The increase of this white blood cell in the body can directly affect the function of some important organs and affect the production of normal and healthy blood cells. Because of the malignant proliferation of tumor cells, inhibition of red blood cells and platelets hemostasis, and even not enough normal white blood cells against infection, it is easy to suffer abrasions, bleeding, infection. The main treatment includes the following several kinds of chemotherapy, radiotherapy, target therapy, and traditional Chinese medicine treatment. Bone marrow transplantation is needed in some high-risk patients. In the past 10 years, along with the development of molecular biology, biological genetics, etiology and pathology of leukemia more in-depth understanding, at the same time the new therapy, new drug discovery and the use of traditional Chinese medicine, which has greatly improved the prognosis of leukemia. "Leukemia is incurable disease" has become the past. Regular and systematic treatment can make most leukemia patients survive for a long time or even recover. Edit this paragraph of rheumatism treatment Rheumatism is the disease that mainly invades the joints, muscles, bones and joints, such as tendons, ligaments, bursa and fascia. In the concept of modern medicine, rheumatism is the abbreviation of rheumatic disease. It refers to a large group of diseases affecting the bones, muscles and their surrounding soft tissues, such as bursa, tendon, fascia, blood vessel and nerve. Rheumatic diseases include diffuse connective tissue disease (such as systemic lupus erythematosus, Sjogren syndrome, inflammatory myopathy, scleroderma and mixed connective tissue disease, Behcet's disease etc.), systemic vasculitis, spondyloarthropathy (such as ankylosing spondylitis, reactive arthritis, Reiter syndrome), osteoarthritis, osteoporosis osteoporosis and hundreds more involved in bone, joint and connective tissue disease. Arthritis has been an international scientific study of rheumatic diseases for an hundred years. In 1927, the world's five continents established the International Union against rheumatism. In domestic science, rheumatology is a clinical discipline of the youngest, was founded in 1985 of the Chinese Medical Association rheumatism, before and after dozens of domestic large hospitals has established the Department of rheumatology. After several generations of Rheumatology efforts, the level of Rheumatology diagnosis and treatment in China has been catching up with the world advanced level. However, in our country has not yet rheumatism knowledge has been widely popularized, misdiagnosis is still very common, the so-called "secret", quackery counterfeit, inappropriate medicine take advantage of a weak point, exaggerated side effects, so that a considerable proportion of the patients with rheumatism and rheumatism treatment suffer, to build the Department of rheumatism or department of Rheumatology large hospitals can be assured. A variety of rheumatic diseases especially autoimmune rheumatic diseases, often have systemic multi system and multi organ damage, with complicated symptoms, often because of complicated clinical manifestations as Difficult miscellaneous diseases. The course of rheumatism is slow and delayed, and some of them erupt. The diagnosis and treatment are rather complicated and complicated. If the medicine is not used regularly, it will make diagnosis and treatment more difficult. The diagnosis of stem cells requires not only a detailed history and physical examination, but also the examination of various antibodies. The treatment after diagnosis is a long-term process. The majority of rheumatism is difficult to cure, often need long-term or even lifelong medication, although most rheumatism is difficult to cure, but still can be treated, through formal and systematic treatment, most patients can control the disease, relieve symptoms, prevention of disability, quality of life and save the life of Ti Gaosheng. If you suffer from rheumatism, without treatment or treatment, you will often delay your illness, lead to disability and even endanger your life. With the deepening of the study of the pathogenesis of rheumatism, the methods of radical cure of rheumatism, such as stem cell transplantation, are being tested in clinical trials. It is reasonable to believe that rheumatism can be cured in the near future. Edit this episode of overdose Can cause adrenal hyperfunction hyperfunction syndrome. Edit this section of pharmacology and Toxicology Adrenocortical hormone drugs. It has many pharmacological functions such as anti inflammation, anti allergy and inhibiting immunity. (1) anti-inflammatory effect: Glucocorticoids reduce and prevent tissue response to inflammation, thereby reducing the expression of inflammation. (2) immunosuppression: to prevent or inhibit cell-mediated immune response, delayed allergic reactions, and to relieve the expansion of primary immune response. (3) the anti shock effect, Kangdu: glucocorticoids can antagonize endotoxin stimulation on the body, reduce cell damage, play a protective role. Edit this section pharmacokinetics Intramuscular injection of betamethasone sodium phosphate in 1 hour blood concentration peak. The plasma protein binding rate of this product is lower than that of other corticosteroids. Edit this paragraph for storage Shading and airtight preservation. Edit the paragraph package 5 bottles or 10 bottles per bottle. Edit the term of validity of this paragraph Tentative 24 months Edit this paragraph to implement standards State Food and drug administration standard YBH13312006 Edit the approval number of this paragraph Chinese medicine word H20060968 Edit this segment of the manufacturing enterprise Company name: Ma'anshan Fengyuan Pharmaceutical Co., Ltd. Extended reading: One Http://www.bbcayy.com/include/web_info.php id=245 open taxonomy: Medicine, pharmacology, adrenal cortex hormones, glucocorticoids, hormone drugs I try to complete the betamethasone. 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Entry statistics Number of visits: about 11958 times Edit times: 7 historical editions Recent update: 2010-05-24 Creator: 89171666 news Business card theme task: Encyclopedia news: Dream and dream dreams of Chinese and foreign culture Taste life -- eight party food market Misfortune from mouth to mouth -- crayfish and "muscle dissolution"" Shanghai amorous feelings -- romantic journey of new Shanghai The ancient capital of new - old Beijing new special feeling culture Brief introduction of the name of the drug composition traits indications preparation dosage and adverse reactions of taboo specifications pay attention to the treatment of drug overdose of pharmacology and toxicology pharmacokinetics storage packaging leukemia matters of pregnant and lactating women use medication for children aged drug drug interactions in the treatment of rheumatism is valid standard approval number of production enterprises ? 2010 Baidu rights statement