IdiopathicAdultNephroticSyndrome:AClinicopathologicalStudyandResponsetoSteroidinaSub-SaharanAfricanCountryLiShuangDaiQingZhengWeiRepoerters:.ContentIntroductionofNSPatientsandMethodsResultsDiscussionConclusionIdiopathicnephroticsyndrome(NS)isdeterminedbyaproteinuriahigherthan3g/24hassociatedwithhypoalbuminemia,withnokidneyinflammatorylesionsorimmunecomplexdeposits.DefinitionClinicaltranslationpodocyteinjury25%-30%glomerulonephritisinadult50%ofglomerulonephritischronickidneydiseaseAimsofthestudyAEpidemiologyBClinico-biology.CHistologyDTherapeutics&ProgressionprofilePatientsteenyearsofageandaboveNephrologyDepartmentatAristideLeDantecUniversityHospitalduring2001.01to2010.10MethodsDescriptivestudyofdifferentvariablesBiveriatanalysisElectronicquestionnaireelaboratedbyEpiInfo3.3.2versionAnalysisDatacollectionPopulationdistributionResults(156outof202patientswereprimitive(77%)SymptomsLaboratorydetailsRenalbiopsyTreatmentsPrognosisAgethemeanagewas17.7-41.7yearsthegroupof15-25yearswasthemostrepresentativewith46％ofpatientsGendermenrepresented72％(112patients)womenrepresented28％(44patients)PopulationdistributionSymptoms40%63%hypertensionhypertensionwasfoundin63patients.edemaedemawasthemostfrequenttypeofpresentationfoundin98patients.LaboratorydetailsRenalbiopsytreatmentlifestylemeasuresdrugtreatmentsufficentcaloricdiet(100%)fluidrestriction(13.4%)sodiumrestriction(95%)alowpotassiumdiet(5.7%)diuretics(91.5%)antiproteinuricagents(43%)ACE-inhibitors(100%)anticoagulation(8.4%)steroid(95.9%)alone(85.8%)Steroidtherapywithcyclophosphamide(7.6%)withazathioprine(2.5%)Prognosiscompleteremissionpatialremissionrelapse23.7%4.45%5.1%Discussion1423PrevalenceAgeHistologyprogress77%41.2%12%Akpechi’sstudyDeme’studyPrevalenceofidiopathicNSourstudymeanageof29years02Ageourstudyagegroupof25-34yearsDeme’sstudyHistologyFSGS(局灶性节段性肾小球硬化)T.MN(微小病变型)MCD(膜性肾病)45.6%5%43.4%ourstudyDeme’study75%6%12%ThecauseofdifferencerenalbiopsyPROGRESS33%28%ChronickidneydiseaseTheprogresstowardschronickidneydiseasewasnotedin33%.RemissionInourstudytheprogressionwasfavorablewithremissionin57patient.ConclusionANSisfrequentinourcountryB.CRemissionisverylowDCommomlesion→FSGSEarlydiagnosisisimportant此课件下载可自行编辑修改，此课件供参考！部分内容来源于网络，如有侵权请与我联系删除！感谢你的观看！
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