OECDGUIDELINESFORTESTINGOFCHEMICALSFullListofTestGuidelinesJuly2015SECTION1-PHYSICAL-CHEMICALPROPERTIESSummaryofConsiderationsintheReportfromtheOECDExpertGrouponPhysicalChemistryNo.TitleOriginalAdoptionNo.ofUpdatesMostrecentUpdatesupdate101UV-VISAbsorptionSpectra12May19810102MeltingPoint/MeltingRange12May1981127July1995103BoilingPoint12May1981127July1995104VapourPressure12May1981227July199523March2006105WaterSolubility12May1981127July1995106Adsorption/DesorptionUsinga12May1981121January2000BatchEquilibriumMethodPartitionCoefficient(n-octanol/12May1981127July1995water):ShakeFlaskMethodComplexFormationAbilityin12May19810-- WaterDensityofLiquidsandSolids12May1981227July19952October2012110ParticleSizeDistribution/Fibre12May19810-- LengthandDiameterDistributions111HydrolysisasafunctionofpH12May1981113April2004112DissociationConstantsinWater12May19810---113ScreeningTestforThermal12May19810---StabilityandStabilityinAir114ViscosityofLiquids12May198112October2012115SurfaceTensionofAqueous12May1981127July1995Solutions1No.TitleOriginalAdoptionNo.ofUpdatesMostrecentUpdatesupdate116FatSolubilityofSolidandLiquid12May19810SubstancesPartitionCoefficient(n-30March1989113April2004octanol/water),HPLCmethodDeterminationoftheNumber-14June19960-- AverageMolecularWeightandtheMolecularWeightDistributionofPolymersusingGelPermeationChromatographyDeterminationoftheLow14June19960-- MolecularWeightContentofaPolymerUsingGelPermeationChromatographySolution/ExtractionBehavioursof14June1996121January2000PolymersinWaterEstimationoftheAdsorption22January20010---)onSoilandonCoefficient(KocSewageSludgeusingHighPerformanceLiquidChromatography(HPLC)26July20130DeterminationofpH,AcidityandAlkalinityPartitionCoefficient(1-Octanol/23March20060Water):Slow-StirringMethod2SECTION2-EFFECTSONBIOTICSYSTEMSSummaryofConsiderationsintheReportfromtheOECDExpertGrouponEcotoxicologyNo.TitleOriginalAdoptionNo.ofUpdatesMostRecentlyUpdatesUpdated201FreshwaterAlgaand12May198127June198423March2006Cyanobacteria,Growth(correctedonInhibitionTest28July2011)202Daphniasp.Acute12May198124April198413April2004ImmobilisationTest(adoptedasDaphniasp.14-dayReproductionTestincludinganAcuteImmobilisationTest)203Fish,AcuteToxicityTest12May198124April198417July1992204Fish,ProlongedToxicity4April19840DateofdeletionTest:14-DayStudy2April2014205AvianDietaryToxicity4April19840-- Test206AvianReproductionTest4April19840207Earthworm,AcuteToxicity4April19840-- TestsTerrestrialPlants,Growth4April1984119July2006TestActivatedSludge,4April1984122July2010RespirationInhibitionTest(CarbonandAmmoniumOxidation)Fish,Early-LifeStage17July1992126July2013ToxicityTestDaphniamagna21September199823October20082October2012ReproductionTestFish,Short-termToxicity21September19980-- TestonEmbryoandSac-fryStagesHoneybees,AcuteOral21September19980-- ToxicityTest3No.TitleOriginalAdoptionNo.ofUpdatesMostrecentupdatesupdate214Honeybees,AcuteContact21September19980---ToxicityTest215Fish,JuvenileGrowthTest21January20000216SoilMicroorganisms:21January20000NitrogenTransformationTestSoilMicroorganisms:21January20000CarbonTransformationTestSediment-Water13April20040ChironomidToxicityUsingSpikedSedimentSediment-Water13April20040ChironomidToxicityUsingSpikedWaterEnchytraeidReproduction13April20040-- TestLemnasp.Growth23March20060-- InhibitionTestEarthwormReproduction13April20040-- Test(Eiseniafetida/Eiseniaandrei)AvianAcuteOralToxicity22July20100-- TestDeterminationofthe8January20070---activityofanaerobicbacteria-Reductionofgasproductionfromanaerobicallysewagesludge225Sediment-Water16October20070LumbriculusToxicityTestUsingSpikedSediment4No.TitleOriginalAdoptionNo.ofUpdatesMostrecentupdatesupdate226PredatoryMite(Hypoaspis3October20080(Geolaelaps)Aculeifer)ReproductionTestinSoilTerrestrialPlantTest:19July20060VegetativeVigourTestDeterminationof3October20080-- DevelopmentalToxicityofaTestChemicaltoDipteranDungFlies(ScathophagastercorariaL.(Scathophagidae)andMuscaautomnalisDeGeer(Muscidae))FishShortTerm7September200912October2012ReproductionAssay21-DayFishAssay:7September20090AShortTermScreeningAssayforOestrogenicandAndrogenicActivity,andAromataseInhibitionAmphibianMetamorphosis7September20090-- AssayCollembolanReproduction7September20090-- TestinSoilSediment-Water22July20100---ChironomidLife-CycleToxicityTestUsingSpikedWaterorSpikedSedimentFishSexualDevelopment28July20110TestChironomussp.,Acute28July20110ImmobilisationTestFishEmbryoAcute26July20130-- Toxicity(FET)Test5No.OriginalAdoptionNo.ofUpdatesMostrecentTitleupdatesupdate237Honeybee(Apismellifera)26July20130-- LarvalToxicityTest,SingleExposureSediment-free26September20140MyriophyllumspicatumToxicityTestWater-Sediment26September20140MyriophyllumspicatumToxicityTestMedakaExtendedOne-28July20150GenerationReproductionTestLarvalAmphibianGrowth28July20150-- andDevelopmentAssay6SECTION3-DEGRADATIONANDACCUMULATIONSummaryofConsiderationsintheReportfromtheOECDExpertGrouponDegradation/AccumulationNo.TitleOriginalNo.ofUpdatesMostRecentlyAdoptionUpdatesUpdated301ReadyBiodegradability:12May1981117July1992301A:DOCDie-AwayTest(301Fcorrected301B:COEvolutionTest2on26July2013)301C:ModifiedMITITest(I)301D:ClosedBottleTest301E:ModifiedOECDScreeningTest301F:ManometricRespirometryTest302AInherentBiodegradability:Modified12May19810SCASTest302BInherentBiodegradability:Zahn-12May1981117July1992Wellens/EMPATest302CInherentBiodegradability:Modified12May19810(correctedinMITITest(II)2009)303SimulationTest-AerobicSewage12May1981122January2001Treatment:A:ActivatedSludgeUnits;B:Biofilms304AInherentBiodegradabilityinSoil12May19810305BioaccumulationinFish:Aqueousand12May1981214June2October2012DietaryExposure1996306BiodegradabilityinSeawater17July19920307AerobicandAnaerobicTransformation24April20020inSoilAerobicandAnaerobicTransformation24April20020-- inAquaticSedimentSystemsAerobicMineralisationinSurfaceWater13April20040-SimulationBiodegradationTestReadyBiodegradability-COinsealed23March0(correctedon2vessels(HeadspaceTest)200626September2014)7No.TitleOriginalNo.ofUpdatesMostRecentlyAdoptionUpdatesUpdated311AnaerobicBiodegradabilityofOrganic23March0-- CompoundsinDigestedSludge:by2006MeasurementofGasProduction312LeachinginSoilColumns13April2004031316October0---EstimationofEmissionsfromPreservative-TreatedWoodtotheEnvironment:LaboratoryMethodforWoodenCommoditiesthatarenotCoveredandareinContactwithFreshWaterorSeawater3October0---SimulationTeststoAssesstheBiodegradabilityofChemicalsDischargedinWastewater3October0BioaccumulationinSediment-2008dwellingBenthicOligochaetes3October0---PhototransformationofChemicalsin2008Water-DirectPhotolysisBioaccumulationinTerrestrial22July20100-- Oligochaetes8SECTION4-HEALTHEFFECTSSummaryofConsiderationsintheReportfromtheOECDExpertGroupsonShortandLongTermToxicologyNo.TitleOriginalAdoptionNo.ofUpdatesMostRecentlyUpdatesUpdated401AcuteOralToxicity12May1981124FebruaryDateofDeletion:198717December2001402AcuteDermalToxicity12May1981124February1987403AcuteInhalationToxicity12May198117September2009404AcuteDermalIrritation/12May1981317July199228July2015Corrosion24April2002405AcuteEyeIrritation/12May1981324April20022October2012Corrosion24Feb.1987406SkinSensitisation12May1981117July1992407RepeatedDose28-DayOral12May1981227July19953October2008ToxicityStudyinRodentsRepeatedDose90-DayOral12May1981121September1998ToxicityStudyinRodentsRepeatedDose90-DayOral12May1981121September1998ToxicityStudyinNon RodentsRepeatedDoseDermal12May19810---Toxicity:90-DaySubchronicDermalToxicity:12May19810---90-dayStudySubacuteInhalationToxicity:12May198117September200928-DayStudySubchronicInhalation12May198117September2009Toxicity:90-DayStudyPrenatalDevelopmental12May1981122January2001ToxicityStudyOne-GenerationReproduction26May198309No.TitleOriginalAdoptionNo.ofUpdatesMostRecentlyUpdatesUpdatedToxicityStudyTwo-Generation26May1983122January2001ReproductionToxicityStudyToxicokinetics4April1984122July2010418DelayedNeurotoxicityof4April1984127July1995OrganophosphorusSubstancesFollowingAcuteExposureDelayedNeurotoxicityof4April1984127July1995OrganophosphorusSubstances:29-DayRepeatedDoseStudyAcuteOraltoxicity-Fixe17July1992117December2001DoseProcedureReproduction/Developmental27July1995128July2015ToxicityScreeningTestCombinedRepeatedDose22March1996128July2015ToxicityStudywiththeReproduction/DevelopmentalToxicityScreeningTestAcuteOralToxicity-Acute22March1996117December2001ToxicClassMethodNeurotoxicityStudyin21July19970RodentsAcuteOralToxicity:Up-and-21September1998217December23March2006DownProcedure2001(correctedon3October2008)426DevelopmentalNeurotoxicity16October20070- StudySkinAbsorption:invivo13April2004MethodSkinAbsorption:invitro13April2004-- MethodSkinSensitisation:Local24April2002122July201010No.TitleOriginalAdoptionNo.ofUpdatesMostRecentlyUpdatesUpdatedLymphNodeAssayinvitroSkinCorrosion:13April2004226July201328July2015TranscutaneousElectricalResistanceTest(TER)invitroSkinCorrosion:13April2004326July201328July2015ReconstructedHuman26Sept.2014Epidermis(RHE)Testinvitro3T3NRU13April20040-- PhototoxicityTestinvitroMembraneBarrier19July2006128July2015TestMethodforSkinCorrosionAcuteInhalationToxicity-7September20090AcuteToxicClassMethodBovineCornealOpacityand7September2009126July2013PermeabilityTestMethodfor(correctedin2010)IdentifyingOcularCorrosivesandSevereIrritantsIsolatedChickenEyeTest7September2009126July2013MethodforIdentifyingOcularCorrosivesandSevereIrritantsinvitroSkinIrritation:22July2010226July201328July2015ReconstructedHumanEpidermisTestMethod16October20070UterotrophicBioassayinRodents:Ashort-termscreeningtestforoestrogenicproperties7September20090---HershbergerBioassayinRats:Ashort-termScreeningAssayfor(Anti)AndrogenicProperties442A22July20100SkinSensitization:LocalLymphNodeAssay:DA11No.TitleOriginalAdoptionNo.ofUpdatesMostRecentlyUpdatesUpdated22July20100---442BSkinSensitization:LocalLymphNodeAssay:BrdU-ELISA442CInchemicoskinSensitisation5February20150442DInvitroSkinSensitisation5February20150---443ExtendedOne-Generation28July20110(CorrectedonReproductiveToxicityStudy2October2012)451CarcinogenicityStudies12May198117September2009452ChronicToxicityStudies12May198117September2009453CombinedChronicToxicity/12May198117September2009CarcinogenicityStudiesPerformance-basedTest7September200922October28July2015GuidelineforStably2012TransfectedTransactivationinvitroAssaystoDetectEstrogenReceptorAgonistsandAntagonistsH295RSteroidogenesisAssay28July20110---457BG1LucEstrogenReceptor2October20120TransactivationinvitroAssaytoDetectEstrogenReceptorAgonistsandAntagonists460FluoresceinLeakageTest2October20120MethodforIdentifyingOcularCorrosivesandSevereIrritants12IntroductiontotheOECDTestGuidelinesongenetictoxicologytestingandguidanceontheselectionandapplicationofassaysNo.TitleOriginalAdoptionNo.ofUpdatesMostRecentlyUpdatesUpdated471BacterialReverseMutationTest26May1983121July1997472GeneticToxicology:26May19830Dateofdeletion:Escherichiacoli,ReverseAssay21July1997(MethodmergedwithTG471)473invitroMammalian26May1983221July26September2014ChromosomeAberrationTest1997invivoMammalianErythrocyte26May1983221July26September2014MicronucleusTest1997invivoMammalianBone4April1984221July26September2014MarrowChromosome1997AberrationTestinvitroMammalianCellGene4April1984221July28July2015MutationTest1997GeneticToxicology:Sex-Linked4April19840DateofdeletionRecessiveLethalTestin2April2014DrosophiliamelanogasterGeneticToxicology:Rodent4April1984128July2015DominantLethalTestGeneticToxicology:invitro23October19860DateofdeletionSisterChromatidExchange2April2014assayinMammalianCellsGeneticToxicology:23October19860DateofdeletionSaccharomycescerevisiae,Gene2April2014MutationAssayGeneticToxicology:23October19860DateofdeletionSaccharomycescerevisiae,2April2014MitoticRecombinationAssayGeneticToxicology:DNA23October19860DateofdeletionDamageandRepair,2April2014UnscheduledDNASynthesisinMammalianCellsinvitro13No.TitleOriginalAdoptionNo.ofUpdatesMostRecentlyUpdatesUpdated483MammalianSpermatagonial23October1986221July28July2015ChromosomalAberrationTest1997484GeneticToxicology:Mouse23October19860DateofdeletionSpotTest2April2014485GeneticToxicology:Mouse23October19860-- HeritableTranslocationAssayUnscheduledDNASynthesis21July19970---(UDS)TestwithMammalianLiverCellsinvivoinvitroMammalianCell22July2010126September2014MicronucleusTestTransgenicRodentSomaticand28July2011126July2013GermCellGeneMutationAssaysinvivoMammalianAlkaline22September20140CometAssayShort-timeExposureforthe28July20150DetectionofChemicalsCausingSeriousEyeDamage,andChemicalsNotRequiringClassificationforSeriousEyeDamageorEyeIrritationReconstructedHumanCornea-28July20150-- likeEpitheliumfortheDetectionofChemicalsNotRequiringClassificationandLabellingforEyeIrritationorSeriousEyeDamageInvitroThymidineKinase28July20150-- MutationTestHumanRecombinantEstrogen28July20150ReceptorBindingAssay14SECTION5-OTHERTESTGUIDELINESIntroductiontoOECDTestGuidelinesonpesticideresidueschemistrysection5-PartaPartA:PesticideResidueChemistryNo.TitleOriginalAdoptionNo.ofUpdatesMostRecentlyUpdatesUpdated501MetabolisminCrops10January20070502MetabolisminRotationalCrops10January20070503MetabolisminLivestock10January20070504ResiduesinRotationalCrops10January20070(LimitedFieldStudies)505ResiduesinLivestock10January20070StabilityofPesticideResiduesin50616October20070StoredCommoditiesNatureofthePesticideResiduesin16October20070-- ProcessedCommodities-HighTemperatureHydrolysisMagnitudeofPesticideResiduesin3October20080ProcessedCommoditiesCropFieldTrial7September2009015
本文档为【OECDGUIDELINESFORTESTINGOFCHEMICALS】，请使用软件OFFICE或WPS软件打开。作品中的文字与图均可以修改和编辑，
图片更改请在作品中右键图片并更换，文字修改请直接点击文字进行修改，也可以新增和删除文档中的内容。
该文档来自用户分享，如有侵权行为请发邮件ishare@vip.sina.com联系网站客服，我们会及时删除。
[版权声明] 本站所有资料为用户分享产生，若发现您的权利被侵害，请联系客服邮件isharekefu@iask.cn，我们尽快处理。
本作品所展示的图片、画像、字体、音乐的版权可能需版权方额外授权，请谨慎使用。
网站提供的党政主题相关内容(国旗、国徽、党徽..)目的在于配合国家政策宣传，仅限个人学习分享使用，禁止用于任何广告和商用目的。
浙公网安备 33021202002483