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Despite concerns that have been expressed about possible health risks from high intake of vitamin E, a new review concludes that biological mechanisms exist to routinely eliminate excess levels of the vitamin, and they make it almost impossible to take a harmful amount. No level of vitamin E in the diet or from any normal use of supplements should be a concern, according to an expert from the Linus Pauling Institute at Oregon State University. The review was just published in the Journal of Lipid Research.
"I believe that past studies which have alleged adverse(相反的) consequences from vitamin E have misinterpreted the data," said Maret Traber, an internationally recognized expert on this micronutrient and professor in the OSU College of Public Health and Human Sciences.
"Taking too much vitamin E is not the real concern," Traber said. "A much more important issue is that more than 90 percent of people in the U.S. have inadequate levels of vitamin E in their diet."
Vitamin E is an antioxidant and a very important nutrient for proper function of many organs, nerves and muscles, and is also an anticoagulant(抗凝剂) that can reduce blood clotting. It can be found in oils, meat and some other foods, but is often consumed at inadequate dietary levels, especially with increasing emphasis on low-fat diets.
In the review of how vitamin E is metabolized, researchers have found that two major systems in the liver work to control the level of vitamin E in the body, and they routinely excrete excessive amounts. Very high intakes achieved with supplementation only succeed in doubling the tissue levels of vitamin E, which is not harmful.
"Toxic levels of vitamin E in the body simply do not occur," Traber said. "Unlike some other fat-soluble vitamins such as vitamins A and D, it's not possible for toxic levels of vitamin E to accumulate in the liver or other tissues."
Vitamin E, because of its interaction with vitamin K, can cause some increase in bleeding, research has shown. But no research has found this poses a health risk.
On the other hand, vitamin E performs many critical roles in optimum health. It protects polyunsaturated fatty acids from oxidizing, may help protect other essential lipids, and has been studied for possible value in many degenerative diseases. Higher than normal intake levels may be needed for some people who have certain health problems, and smoking has also been shown to deplete vitamin E levels.
Traber said she recommends taking a daily multivitamin that has the full RDA of vitamin E, along with consuming a healthy and balanced diet.
得出结论认为,尽管维生素E的摄入量高的,新的审查
表
关于同志近三年现实表现材料材料类招标技术评分表图表与交易pdf视力表打印pdf用图表说话 pdf
示关注可能的健康风险的担忧已存在的生物机制,定期消除过量的维生素,而且他们几乎不可能采取一种有害的金额。在饮食或从任何正常使用的补充维生素E水平应该是一个问题,根据在俄勒冈州立大学莱纳斯·鲍林研究所专家。脂质研究杂志刚刚出版的审查。
“我相信,过去的研究已涉嫌不良(相反的)维生素E的后果有误解的数据,微量营养素和俄勒冈州立大学公共卫生学院及人文科学的教授,国际公认的专家MARET特拉伯说:“。
“服用过多的维生素E,是不是真正的关注,特拉伯说。” “一个更重要的问题是,在美国90%以上的人有他们的饮食中维生素E的含量不足。”
维生素E是一种抗氧化剂和许多器官,神经和肌肉的正常功能的一个非常重要的营养素,也是,可以降低血液凝固的抗凝血剂(抗凝剂)。可以发现,在油中,肉类和一些其他的食物,但往往是消耗于饮食水平不足,特别是与低脂肪饮食日益重视。
维生素E是如何代谢的审查,研究人员已发现,在肝脏工作的两大系统来控制维生素E在体内的水平,他们经常排泄过量。只许成功,取得了非常高的摄入量补充维生素E,这是不是有害的组织水平增加一倍。
维生素E在体内的毒性水平的,根本就没有发生,“特拉伯说。” “不像其他一些脂溶性维生素,如维生素A和D,这是不可能有毒的维生素E水平,积累在肝脏或其他组织。”
因为其与维生素K,维生素E,可能会导致一些出血增加,有研究表明。但是,没有研究已经发现这种情况构成健康风险。
另一方面,维生素E执行许多关键作用,在最佳的健康。保护多不饱和脂肪酸的氧化,可能有助于保护其他必要的脂质,并已在许多退化性疾病研究的可能值。高于正常摄入量可能需要对某些人来说有一定的健康问题,吸烟也被证明耗尽维生素E水平。
特拉伯说,她建议每天服用多种维生素,有充分的RDA的维生素E,随着消费健康和均衡的饮食。
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