维生素D可使患糖尿病的女性降低血压

海量资料下载 免费学习英语 www.englishvip.com/xinlw.htm （申请网址） In women who have type 2 diabetes and show signs of depression, vitamin D supplements significantly lowered blood pressure and improved their moods, according to a pilot study at Loyola University Chicago Niehoff School of Nursing. Vitamin D even helped the women lose a few pounds.   The study was presented at the American Diabetes Association 73rd Scientific Sessions in Chicago.   "Vitamin D supplementation potentially is an easy and cost-effective therapy, with minimal side effects," said Sue M. Penckofer, PhD, RN, lead author of the study and a professor in the Niehoff School of Nursing. "Larger, randomized controlled trials are needed to determine the impact of vitamin D supplementation on depression and major cardiovascular（心血管的）risk factors among women with Type 2 diabetes."   Penckofer recently received a four-year, $1.49 million grant from the National Institute of Nursing Research at the National Institutes of Health to do such a study. Penckofer and her Loyola co-investigators plan to enroll 180 women who have type 2 diabetes, symptoms of depression and insufficient levels of vitamin D. Women will be randomly assigned to receive either a weekly vitamin D supplementation (50,000 International Units) or a matching weekly placebo for six months. The study is titled "Can the Sunshine Vitamin Improve Mood and Self Management in Women with Diabetes?   About 1 in 10 people in the United States has diabetes, and the incidence is projected to increase to 1 in 4 persons by 2050. Women with type 2 diabetes have worse outcomes than men. The reason may be due to depression, which affects more than 25 percent of women with diabetes. Depression impairs a patient's ability to manage her disease by eating right, exercising, taking medications, etc.   Many Americans do not get enough vitamin D, and people with diabetes are at especially high risk for vitamin D insufficiency or deficiency. Reasons include limited intake of foods high in vitamin D, obesity, lack of sun exposure and genetic variations.   The pilot study included 46 women who were an average age of 55 years, had diabetes an average of 8 years and insufficient blood levels of vitamin D (18 ng/ml). They took a weekly dose (50,000 International Units) of vitamin D. (By comparison, the recommended dietary allowance for women 51 to 70 years is 600 IU per day.)   After six months, their vitamin D blood levels reached sufficient levels (average 38 ng/ml) and their moods improved significantly. For example, in a 20-question depression symptom survey, scores decreased from 26.8 at the beginning of the study (indicating moderate depression) to 12.2 at six months (indicating no depression. (The depression scale ranges from 0 to 60, with higher numbers indicating more symptoms of depression.)   Blood pressure also improved, with the upper number decreasing from 140.4 mm Hg to 132.5 mm Hg. And their weight dropped from an average of 226.1 pounds to 223.6 pounds.   Penckofer is internationally known for her research on vitamin D, diabetes and depression. In October, she will be inducted as a Fellow in the American Academy of Nursing for her scientific contributions in improving the health and quality of life of women with chronic disease. And she recently was appointed as the first nurse researcher to the Chicago Diabetes Center for Translational Research.   Co-authors of the study are Todd Doyle, PhD, Patricia Mumby, PhD, Mary Byrn, Mary Ann Emanuele, MD and Diane Wallis, MD. 在谁的妇女有2型糖尿病和抑郁症的迹象显示，补充维生素D显着降低血压，并改善他们的情绪，根据美国芝加哥Loyola大学尼霍夫护理学院试点研究。维生素D甚至帮助妇女失去了几磅。   这项研究发表于美国糖尿病协会第73届科学会议在芝加哥。   “补充维生素D可能是一个简单的和具有成本效益的治疗，以最小的副作用，说：”这项研究的主要作者和尼霍夫护理学院教授的苏M. Penckofer，博士，注册护士，。“较大的，随机对照试验，以确定需要补充维生素D对抑郁症和主要心血管的影响（心血管的）危险因素与2型糖尿病的妇女。“   Penckofer最近收到了一个为期四年，价值1.49万美元的赠款从国家护理研究机构在美国国立卫生研究院做这样的研究。Penckofer和她的的洛约拉合作调查 计划 项目进度计划表范例计划下载计划下载计划下载课程教学计划下载 招收180名妇女，2型糖尿病，抑郁症的症状和水平不足，维生素D的妇女将被随机分配接受每周维生素D补充剂（50000国际单位）或每周匹配安慰剂六个月。这项研究名为“阳光维生素可以改善情绪和女性糖尿病患者的自我管理？   关于1 10人在美国有糖尿病，且发病率到2050年预计将增加至4人1。2型糖尿病的妇女比男性预后较差。其原因可能是由于抑郁，影响超过25％的妇女患有糖尿病。抑郁症会损害患者的能力来管理她的病通过正确的饮食，运动，服用药物等。   许多美国人没有得到足够的维生素D，患有糖尿病的人尤其是维生素D不足或缺乏的高风险。原因包括限制摄入含维生素D高的食物，肥胖，缺乏阳光下暴晒和遗传变异。   试点研究包括46名妇女，平均年龄为55岁，患有糖尿病平均8岁和不足，血液中的维生素D（18毫微克/毫升）。他们把每周一次的剂量（50,000国际单位）的维生素D（通过比较，女性51至70岁的建议摄取量是每天600 IU）。   六个月后，他们的维生素D的血药浓度达到足够的水平（平均为38毫微克/毫升），并显着改善他们的情绪。例如，在一个20个问题的抑郁症状调查中，得分从26.8下降表示中度抑郁症）的研究（年初至12.2，在6个月（表示没有抑郁症（抑郁量表从0到60不等，数字越大，说明更多的抑郁症状。）   血压也有所改善，与上数从140.4毫米汞柱下降到132.5毫米汞柱。自己的体重下降从226.1磅平均到223.6磅。   她的研究维生素D，糖尿病和抑郁症是国际知名的Penckofer。在10月，她将被引导为美国科学院院士，她的科学贡献，在改善与慢性疾病的妇女的生活质量和健康护理。最近，她被任命为芝加哥糖尿病转化研究中心研究员的第一位护士。   研究的共同作者，帕特里夏的M.托德·多伊尔，博士，博士，玛丽Byrn，玛丽安·埃马努埃莱，MD和黛安·沃利斯，MD。 “成千上万人疯狂下载。。。。。。 更多价值连城的绝密英语学习资料， 洛基内部秘密英语，技巧，策略 请在 网上 申请报名” 洛基国际英语 竭诚为您服务